Etomidate vs. Propofol: Data Sheet, Study Flow, Data Collection Tips, FAQs
 

Overview: A study designed to determine the efficacy and safety of propofol vs. etomidate in procedural sedations of fracture and dislocation reductions.

Study Endpoints: 1. Respiratory depression as assessed by ETCO2 2. Mental status as assessed by BIS, OAAS, and patient report.

Eligible Patients: Adult (≥18 y.o.) patients undergoing a procedural sedation for any reason.

Study Design: Prospective, randomized clinical trial.
 

Anticipated Benefits: BIS and ETCO2 monitoring mandated by the study may improve safety of procedure.
 

Potential Risks: the usual risks associated with procedural sedation.
 

Research Associate’s Role: The RA is responsible for identifying, enrolling, and collecting data from eligible patients for this study.  The RA is in charge of setting up and putting away the BIS and End-Tidal CO₂ monitors used to obtain data during the procedure.  After the study, the RA conducts interviews of the physician and the patient.
 

Physician’s Role: The RA will ask you to notify them of any conscious sedations being performed so that they may enter the patient into the study.  You will be asked to perform the sedation using either propofol or etomidate. Once the procedure is over, you will be asked to complete a short questionnaire about the success of the procedure and the time it took for the patient to return to baseline mental status.
 

Location of Study Packets: Team Center B